Discovery Research
Axela’s dotLab and Ziplex system will have special appeal to life scientists conducting basic protein and genetics discovery research in academia, government research institutions, and pharmaceutical companies and are involved in:
- Basic proteomics and genomics research
- Working with biomarkers in pre-clinical and clinical drug discovery programs
- Using technologies such as ELISA and Western blot for protein identification and quantitation, and technologies such as surface plasmon resonance (SPR) for immunoassay development and optimization, and protein interaction analysis
- Routine analysis of gene subsets discovered on genome wide discovery arrays
- Antibody and protein production
and who need:
- Accessible multiplex protein and gene expression studies at the bench top
- Rapid and/or real time results to enable research decisions
- Versatility in assay formats
- Direct use of complex samples
- Platform flexibility
- Ease of assay design
- Economical capital and cost per data point
Applications
dotLab mX System
Biomolecular Interactions
- Detection and analysis of protein-protein interactions
Epitope mapping and Protein Complexes
- Allows for the rapid determination of antibody pairing and epitope mapping, and of protein primary and ternary structures
Expression Monitoring Quantitation
- Provides high sensitivity (picomolar level) and dynamic range (>7 logs) without serial dilutions
Assay Development
- Rapid optimization of antibody ranking and pairing, buffer conditions, and cross reactivity
Ziplex System
Transfer of gene subsets from genome wide discovery assays
- Provides ability for routine and low cost analysis of gene expression on focused microarrays
Single platform for both genomics and proteomics research
- Available Xpress Chips for studying the gene expression of known genes involved in oncology, inflammation and metabolic disorders
- Protein microarrays for discovery research and biomarker analysis (Available now through our collaborator program)
The Axela Advantage
- One system for all stages of development and rapid assays
- Rapid assays results drive research decisions
- Customizable dotLab panels and Ziplex TipChips
- Maximum information from a single experiment
- Reduces the need for purification and sample preparation
- Large dynamic range with high sensitivity
- Avoids the cost and time delay associated with sending samples to the core lab